Ensuring Cell Line Stability for Consistent Lentiviral Vector Production Genetic Engineering for Stability
Time: 4:00 pm
day: Conference Day One
Details:
- Discuss techniques for stabilizing producer cell lines, including stable transfection and selection methods, to ensure consistent vector yield and quality over extended production cycles
- Minimizing Genetic Drift: Explore strategies to reduce genetic variation and loss of transgene expression over time, which can lead to inconsistent LVV production and reduced quality
- Long-Term Culture Conditions: Highlight the importance of optimizing culture conditions (e.g., media, cell density) and process monitoring to maintain cell line performance and stability during large-scale, long-term production
