Evolving AAV Manufacturing: Comparing Transient Transfection & Producer Cell Line Platforms to Enable Scalable Gene Therapy Production

• Managing transient transfection variability at scale to improve manufacturing consistency, reduce operational complexity and support reliable pipeline delivery
• Comparing transient transfection and producer cell line platforms to inform technology selection decisions based on technical, operational and economic requirements
• Optimizing producer cell line clone selection workflows through scale-down screening models to accelerate high-performing clone identification and process development

Speakers:

Ying Liu

Associate Director, Cell Culture & Process Development, Genomic Medicine Unit

Sanofi