Manufacturing & QC Considerations for TfR1-Targeted AAV Capsids: Balancing Innovation with Process Robustness

• Identifying key bottlenecks in purification and how adjustments in chromatography and filtration improve recovery and yield
• Evaluating the role of advanced analytical methods in confirming identity and consistency
• Sharing lessons on establishing platform QC methods that remain predictive and reproducible when applied to engineered capsids

Speakers:

Von Wiltman

Associate Director - Technical Operations

Apertura Gene Therapy