Optimizing Viral Amplification Efficiency: Enhancing Transfection and Packaging for Higher Yields
Time: 12:30 pm
day: Conference Day One
Details:
- Improving Transfection Efficiency: Explore strategies to enhance transfection methods, focusing on optimizing DNA quality, selecting the right transfection reagents, and fine-tuning cell types to maximize the efficiency of viral vector production
- Streamlining Viral Packaging: Discuss the critical role of packaging cell lines in viral vector production, and how optimizing packaging conditions can increase both yield and infectivity, addressing variability in packaging efficiency
- Scaling Amplification for Consistency: Address the challenges of scaling viral amplification from lab to production scale, including maintaining high transfection and packaging efficiency while minimizing batch-to-batch variability and optimizing vector potency
