Andrew Tustian
Executive Director, Preclinical Manufacturing & Process Development Regeneron Pharmaceuticals
Seminars
Thursday 25th February 2027
Optimizing Anion Exchange Chromatography Strategies to Enhance AAV Empty-Full Capsid Separation Efficiency
3:15 pm
- Establishing anion exchange chromatography as a critical purification strategy to maximize empty-full capsid separation across AAV manufacturing processes
- Comparing multiple anion exchange chromatography approaches to select the most effective strategy for specific AAV process requirements
- Aligning anion exchange method selection with serotype characteristics, impurity load and partial capsid distribution to improve purification performance
