Aziza Manceur
Research Officer National Research Council Canada
Seminars
Thursday 25th February 2027
Implementing Packaging & Producer Cell Lines to Eliminate Plasmid Transfection Complexity & Reduce Manufacturing Costs
2:45 pm
- Evaluating stable producer cell lines as alternatives to transient transfection for simplified GMP manufacturing, eliminating the expensive plasmid costs and transfection variability that drive up manufacturing expenses
- Assessing quality comparisons between transient transfection and stable cell line-derived vectors, ensuring product comparability and regulatory acceptability when transitioning platforms
- Understanding cost-benefit analysis including development timelines, productivity and regulatory considerations, making informed decisions on when producer cell line investment delivers meaningful return
