Brooke Hodge
Upstream Process Development Engineer Astellas Pharma
Seminars
Thursday 25th February 2027
Improving Triple Transfection Consistency to Reduce Batch-to-Batch Variability & Minimize Manufacturing Risk
9:30 am
- Addressing transfection cocktail stability challenges and time-sensitive nature of plasmid-reagent complexation, preventing the batch failures that waste resources and delay clinical supply
- Optimizing mixing and pumping parameters to ensure uniform delivery of transfection complexes to cells, achieving consistent yields and quality attributes that support reliable manufacturing
- Implementing quality measurements of transfection cocktails before use to predict and prevent batch failures, reducing the costly losses that occur when transfection variability impacts downstream performance
