Michael Datillo

Company: Johnson & Johnson Services, Inc

Job title: Senior Investigator, Lentiviral Vector Manufacturing Excellence

Seminars:

Ensuring Cell Line Stability for Consistent Lentiviral Vector Production Genetic Engineering for Stability 4:00 pm

Discuss techniques for stabilizing producer cell lines, including stable transfection and selection methods, to ensure consistent vector yield and quality over extended production cycles Minimizing Genetic Drift: Explore strategies to reduce genetic variation and loss of transgene expression over time, which can lead to inconsistent LVV production and reduced quality Long-Term Culture Conditions: Highlight the…Read more

day: Conference Day One

Overcoming Downstream Impurity Challenges in Lentiviral Manufacturing: A Point-of-Use Approach 4:00 pm

Sharing insights from the point of use on common impurities faced during lentiviral vector production, such as residual host cell proteins, DNA, and product-related contaminants, and their practical impact on downstream processes Highlighting effective, on-the-ground strategies for dealing with impurities, from optimizing filtration methods to implementing process control techniques that ensure the purity of lentiviral…Read more

day: Conference Day Two